Bowel Disease
نویسنده
چکیده
CROHN DISEASE Pathology Crohn disease is characterized by segmental, transmural, granulomatous inflammatory changes that can occur anywhere along the gastrointestinal tract from the mouth to the perianal area. Disease of the terminal ileum is present in 80% of patients with Crohn disease, and 50% of patients have ileocolitis. Approximately 33% and 20% of patients demonstrate only ileal and colonic involvement, respectively. The finding of skip lesions between areas of normal bowel and cobblestoning of the intestinal mucosa is classic for Crohn disease. Chronic inflammation commonly leads to bowel stenosis.
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